Hormonal Balance (Menopause) 2017-05-04T11:11:55+00:00

Hormonal Balance (Menopause)

Many women experience physical and emotional symptoms during menopause, typically during her mid-40s. This is caused by imbalanced hormones (a lowered production of the female sex hormones estrogen and progesterone).
Below are common symptoms associated with menopause. They generally occur during the  premenopausal stage.
  • Irregular mood swing
  • Night sweats
  • Increased anxiety or irritability
  • Muscle and joint pain
  • Fatigue and dizziness
  • Hair loss or thinning
  • Difficulty in sleeping, lethargy

How does VF Nano Placenta Extract help to relieve menopause symptoms?

VF Nano Placenta Extract relieves shoulder stiffness in women experiencing menopause.

A open-label, randomized, controlled study was conducted on sixty-six climacteric women (33 each in the control and study groups) with shoulder stiffness. Control subjects received an oral herbal remedy used to alleviate climacteric symptoms, and study subjects received porcine placenta extract orally for 24 weeks. The VAS (Visual Analog Scale) score measured improved by 76.4%. Results show that porcine placenta extract is useful as an oral supplement for relieving shoulder stiffness in climacteric women.
K Koike et al. Climacteric. 2013 Aug;16(4):447-52

VF Nano Placenta Extract help to improve mild menopausal symptoms including vasomotor symptoms (hot flushes, night sweats), psychological symptoms (depressive) and somatic symptoms (heart, muscle and joint discomfort)

In a 12-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study, 50 climacteric Japanese women were randomized 1 : 1 to oral porcine placenta extract (300 mg/day) or placebo. Menopausal symptoms were evaluated by using the Simplified Menopausal Index (SMI)*, as were serum estradiol (E2) and follicle stimulating hormone (FSH) levels. Blood biochemical and cellular and urinary tests were done to evaluate safety aspects of repeated oral administration of porcine placenta extract.
The total Simplified Menopausal Index (SMI) score of the porcine placenta extract group improved significantly after 12 weeks as compared to the placebo group. This score and three subscores (vasomotor, psychological, and somatic symptoms) significantly improved at 8 and/or 12 weeks compared with the initial values in the porcine placenta extract group (p < 0.05). No improvement was observed in the E2 and FSH levels.
* Simplified Menopausal Index (SMI) is a comprehensive tool to examine menopausal symptoms
K Koike et al. Climacteric. 2013 Aug;16(4):447-52

Postmenopausal osteoporosis

Postmenopausal osteoporosis is characterized by a net bone loss due to an imbalance between osteoclast-mediated bone resorption and osteoblast-mediated bone formation. There is a direct relationship between the lack of estrogen during menopause and the development of osteoporosis. Estrogen is a well-known regulator of bone metabolism, postmenopausal osteoporosis, and the morbidity which are major health problems in elderly women. Osteoporosis increases susceptibility to bone fractures and reduces quality of life. Hormone replacement therapy (HRT) has proven to be efficacious in preventing bone loss and reducing the incidence of skeletal fractures in postmenopausal women but has several side effects. Other remedies such as porcine placenta extract has been used to prevent and treat postmenopausal osteoporosis.
Up to 20% of bone loss happens in the 5 to 7 years just after menopause.
1 in 2 women over age 50 will have an osteoporosis-related fracture in her lifetime
Alkaline phosphate (ALP) is a marker of osteoblast differentiation and bone formation. Alkaline phosphate is significantly increase the serum ALP level.

Figure below show that porcine placenta extract increase the bone mineral density